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PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression

The progression of cancer from localized to metastatic disease is the primary cause of morbidity and mortality. The interplay between the tumor and its microenvironment is the key driver in this process of tumor progression. In order for tumors to progress and metastasize they must reprogram the cel...

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Detalles Bibliográficos
Autores principales: Sui, Lufei, Wang, Suming, Ganguly, Debolina, El Rayes, Tyler P., Askeland, Cecilie, Børretzen, Astrid, Sim, Danielle, Halvorsen, Ole Johan, Knutsvik, Gøril, Arnes, Jarle, Aziz, Sura, Haukaas, Svein, Foulkes, William D., Bielenberg, Diane R., Ziemys, Arturas, Mittal, Vivek, Brekken, Rolf A., Akslen, Lars A., Watnick, Randolph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794699/
https://www.ncbi.nlm.nih.gov/pubmed/36575174
http://dx.doi.org/10.1038/s41467-022-35649-9