Cargando…

Mitochondrial PARP1 regulates NAD(+)-dependent poly ADP-ribosylation of mitochondrial nucleoids

PARPs play fundamental roles in multiple DNA damage recognition and repair pathways. Persistent nuclear PARP activation causes cellular NAD(+) depletion and exacerbates cellular aging. However, very little is known about mitochondrial PARP (mtPARP) and poly ADP-ribosylation (PARylation). The existen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jong-Hyuk, Hussain, Mansoor, Kim, Edward W., Cheng, Shang-Jung, Leung, Anthony K. L., Fakouri, Nima Borhan, Croteau, Deborah L., Bohr, Vilhelm A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794712/ https://www.ncbi.nlm.nih.gov/pubmed/36473936 http://dx.doi.org/10.1038/s12276-022-00894-x

Ejemplares similares

Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis
por: Fakouri, Nima Borhan, et al.
Publicado: (2017)

Mitochondrial NAD(+) Controls Nuclear ARTD1-Induced ADP-Ribosylation
por: Hopp, Ann-Katrin, et al.
Publicado: (2021)

Author Correction: Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis
por: Fakouri, Nima Borhan, et al.
Publicado: (2018)

The β-NAD(+) salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation
por: Henderson, David J.P., et al.
Publicado: (2017)

PARPs and ADP-ribosylation: 60 years on
por: Kraus, W. Lee
Publicado: (2020)

Regulation of Glucose Metabolism by NAD(+) and ADP-Ribosylation
por: Hopp, Ann-Katrin, et al.
Publicado: (2019)

PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
por: Chen, Qian, et al.
Publicado: (2018)

Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins
por: Alemasova, Elizaveta E, et al.
Publicado: (2019)

Role of NAD(+) and ADP-Ribosylation in the Maintenance of the Golgi Structure
por: Mironov, Alexander, et al.
Publicado: (1997)

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling
por: Okur, Mustafa N., et al.
Publicado: (2020)

Mono-ADP-ribosylation by PARP10 and PARP14 in genome stability
por: Dhoonmoon, Ashna, et al.
Publicado: (2023)

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)
por: Otto, Helge, et al.
Publicado: (2005)

The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context
por: Kutuzov, M. M., et al.
Publicado: (2021)

A ribose-functionalized NAD(+) with unexpected high activity and selectivity for protein poly-ADP-ribosylation
por: Zhang, Xiao-Nan, et al.
Publicado: (2019)

CDK2 phosphorylation of Werner protein (WRN) contributes to WRN’s DNA double‐strand break repair pathway choice
por: Lee, Jong‐Hyuk, et al.
Publicado: (2021)

PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities
por: Đukić, Nina, et al.
Publicado: (2023)

EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer
por: Yamaguchi, Hirohito, et al.
Publicado: (2017)

Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis
por: Chen, Qian, et al.
Publicado: (2022)

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
por: Altmeyer, Matthias, et al.
Publicado: (2009)

Poly(ADP-Ribosyl) Code Functions
por: Maluchenko, N. V., et al.
Publicado: (2021)

PARP-1 may be involved in hydroquinone-induced apoptosis by poly ADP-ribosylation of ZO-2
por: Liu, Jiaxian, et al.
Publicado: (2017)

PARP1 and Poly(ADP-ribosyl)ation Signaling during Autophagy in Response to Nutrient Deprivation
por: Rodríguez-Vargas, José Manuel, et al.
Publicado: (2019)

Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase
por: Westera, Liset, et al.
Publicado: (2019)

Insight into DNA substrate specificity of PARP1-catalysed DNA poly(ADP-ribosyl)ation
por: Matta, Elie, et al.
Publicado: (2020)

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation
por: Zarkovic, Gabriella, et al.
Publicado: (2018)

The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions
por: Fehr, Anthony R., et al.
Publicado: (2020)

PARPs and ADP-Ribosylation in Chronic Inflammation: A Focus on Macrophages
por: Santinelli-Pestana, Diego V., et al.
Publicado: (2023)

CROSSTALK BETWEEN UBIQUITINATION AND ADP-RIBOSYLATION IN THE MAINTENANCE OF MITOCHONDRIAL HOMEOSTASIS
por: Perissi, Valentina
Publicado: (2022)

The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy
por: Li, Zhenzhen, et al.
Publicado: (2021)

Poly(ADP-ribosyl)ation in mammalian ageing
por: Beneke, Sascha, et al.
Publicado: (2007)

ADP-ribosylation of RNA in mammalian cells is mediated by TRPT1 and multiple PARPs
por: Weixler, Lisa, et al.
Publicado: (2022)

Multiomics analysis of the NAD(+)–PARP1 axis reveals a role for site-specific ADP-ribosylation in splicing in embryonic stem cells
por: Jones, Aarin, et al.
Publicado: (2022)

PARP1 ADP-ribosylates lysine residues of the core histone tails
por: Messner, Simon, et al.
Publicado: (2010)

ADP Ribosylation by PARP-1 Suppresses HOXB7 Transcriptional Activity
por: Wu, Xinyan, et al.
Publicado: (2012)

PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation
por: Torretta, Archimede, et al.
Publicado: (2023)

Privileged Scaffolds for Potent and Specific Inhibitors of Mono-ADP-Ribosylating PARPs
por: Nizi, Maria Giulia, et al.
Publicado: (2023)

PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages
por: Chiu, Ling-Ya, et al.
Publicado: (2022)

PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment
por: Maresca, C., et al.
Publicado: (2023)

The Promise of Proteomics for the Study of ADP-Ribosylation
por: Daniels, Casey M., et al.
Publicado: (2015)

Regulation of chromatin structure by poly(ADP-ribosyl)ation
por: Beneke, Sascha
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9c3mpjgkupa92n5rtheb744al8