Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models

We previously reported that pentagamavunone-1 (PGV-1) effectively inhibited cell proliferation in many types of human tumors, including pancreatic cancer, by inducing M phase (prometaphase) arrest, senescence, and apoptosis with few side effects. However, a detailed evaluation of the effects of PGV-...

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Detalles Bibliográficos
Autores principales: Kamitani, Naoki, Nakamae, Ikuko, Yoneda-Kato, Noriko, Kato, Jun-ya, Sho, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794715/
https://www.ncbi.nlm.nih.gov/pubmed/36575213
http://dx.doi.org/10.1038/s41598-022-26863-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794715/
https://www.ncbi.nlm.nih.gov/pubmed/36575213
http://dx.doi.org/10.1038/s41598-022-26863-y

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