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Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models
We previously reported that pentagamavunone-1 (PGV-1) effectively inhibited cell proliferation in many types of human tumors, including pancreatic cancer, by inducing M phase (prometaphase) arrest, senescence, and apoptosis with few side effects. However, a detailed evaluation of the effects of PGV-...
Autores principales: | Kamitani, Naoki, Nakamae, Ikuko, Yoneda-Kato, Noriko, Kato, Jun-ya, Sho, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794715/ https://www.ncbi.nlm.nih.gov/pubmed/36575213 http://dx.doi.org/10.1038/s41598-022-26863-y |
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