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Integrative proteomics and metabolomics approach to identify the key roles of icariin-mediated protective effects against cyclophosphamide-induced spermatogenesis dysfunction in mice

The alkylating antineoplastic agent cyclophosphamide (CP) is known to be toxic to the male reproductive system, but there are no effective prevention or treatment options. The flavonoid icariin (ICA), which is used in Chinese medicine, has been shown to have a number of biological functions, includi...

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Detalles Bibliográficos
Autores principales: Fang, Chunyan, Ye, Yulong, Yang, Fang, Wang, Fangyue, Shen, Yifeng, Chang, Degui, You, Yaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794755/
https://www.ncbi.nlm.nih.gov/pubmed/36588705
http://dx.doi.org/10.3389/fphar.2022.1040544