Phase Ib/II study of nivolumab combined with palliative radiation therapy for bone metastasis in patients with HER2-negative metastatic breast cancer

Radiation therapy (RT) can enhance the abscopal effect of immune checkpoint blockade. This phase I/II study investigated the efficacy and safety of nivolumab plus RT in HER2-negative metastatic breast cancer requiring palliative RT for bone metastases. Cohort A included luminal-like disease, and coh...

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Detalles Bibliográficos
Autores principales: Takada, Masahiro, Yoshimura, Michio, Kotake, Takeshi, Kawaguchi, Kosuke, Uozumi, Ryuji, Kataoka, Masako, Kato, Hironori, Yoshibayashi, Hiroshi, Suwa, Hirofumi, Tsuji, Wakako, Yamashiro, Hiroyasu, Suzuki, Eiji, Torii, Masae, Yamada, Yosuke, Kataoka, Tatsuki, Ishiguro, Hiroshi, Morita, Satoshi, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794767/
https://www.ncbi.nlm.nih.gov/pubmed/36575361
http://dx.doi.org/10.1038/s41598-022-27048-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794767/
https://www.ncbi.nlm.nih.gov/pubmed/36575361
http://dx.doi.org/10.1038/s41598-022-27048-3

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