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Molecular mechanism of substrate recognition by folate transporter SLC19A1

Folate (vitamin B(9)) is the coenzyme involved in one-carbon transfer biochemical reactions essential for cell survival and proliferation, with its inadequacy causing developmental defects or severe diseases. Notably, mammalian cells lack the ability to de novo synthesize folate but instead rely on...

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Detalles Bibliográficos
Autores principales: Dang, Yu, Zhou, Dong, Du, Xiaojuan, Zhao, Hongtu, Lee, Chia-Hsueh, Yang, Jing, Wang, Yijie, Qin, Changdong, Guo, Zhenxi, Zhang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794768/
https://www.ncbi.nlm.nih.gov/pubmed/36575193
http://dx.doi.org/10.1038/s41421-022-00508-w