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NF-κB1 p50 stabilizes HIF-1α protein through suppression of ATG7-dependent autophagy

The function and underlying mechanisms of p50 in the regulation of protein expression is much less studied because of its lacking of transactivation domain. In this study, we discovered a novel function of p50 in its stabilization of hypoxia-inducible factor 1α (HIF-1α) protein under the condition o...

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Detalles Bibliográficos
Autores principales: Zhu, Junlan, Huang, Shirui, Li, Yang, Xu, Jiheng, Chen, Ruifan, Guo, Mengxin, Qian, Xiaohui, Li, Tengda, Tian, Zhongxian, Jin, Honglei, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794792/
https://www.ncbi.nlm.nih.gov/pubmed/36575197
http://dx.doi.org/10.1038/s41419-022-05521-1