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NF-κB1 p50 stabilizes HIF-1α protein through suppression of ATG7-dependent autophagy
The function and underlying mechanisms of p50 in the regulation of protein expression is much less studied because of its lacking of transactivation domain. In this study, we discovered a novel function of p50 in its stabilization of hypoxia-inducible factor 1α (HIF-1α) protein under the condition o...
Autores principales: | Zhu, Junlan, Huang, Shirui, Li, Yang, Xu, Jiheng, Chen, Ruifan, Guo, Mengxin, Qian, Xiaohui, Li, Tengda, Tian, Zhongxian, Jin, Honglei, Huang, Chuanshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794792/ https://www.ncbi.nlm.nih.gov/pubmed/36575197 http://dx.doi.org/10.1038/s41419-022-05521-1 |
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