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Pretreatment of human retinal pigment epithelial cells with sterculic acid forestalls fenretinide-induced apoptosis
The ratio of saturated to monounsaturated fatty acids, thought to play a critical role in many cellular functions, is regulated by stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Previously, we observed a decrease in both SCD protein and enzy...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794835/ https://www.ncbi.nlm.nih.gov/pubmed/36575190 http://dx.doi.org/10.1038/s41598-022-26383-9 |