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Agrimol B inhibits colon carcinoma progression by blocking mitochondrial function through the PGC-1α/NRF1/TFAM signaling pathway

BACKGROUND: The activation of peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) stimulates the transcription of the downstream target proteins, mitochondrial transcription factor A (TFAM) and nuclear respiratory factor 1 (NRF1), which induces mitochondrial biogenesis and promotes...

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Detalles Bibliográficos
Autores principales: Xiang, Dongyang, Yang, Wenjuan, Fang, Zihan, Mao, Jialei, Yan, Qiuying, Li, Liu, Tan, Jiani, Yu, Chengtao, Qian, Jun, Tang, Dongxin, Pan, Xiaoting, Cheng, Haibo, Sun, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794846/
https://www.ncbi.nlm.nih.gov/pubmed/36591497
http://dx.doi.org/10.3389/fonc.2022.1055126