Cargando…
Agrimol B inhibits colon carcinoma progression by blocking mitochondrial function through the PGC-1α/NRF1/TFAM signaling pathway
BACKGROUND: The activation of peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) stimulates the transcription of the downstream target proteins, mitochondrial transcription factor A (TFAM) and nuclear respiratory factor 1 (NRF1), which induces mitochondrial biogenesis and promotes...
Autores principales: | Xiang, Dongyang, Yang, Wenjuan, Fang, Zihan, Mao, Jialei, Yan, Qiuying, Li, Liu, Tan, Jiani, Yu, Chengtao, Qian, Jun, Tang, Dongxin, Pan, Xiaoting, Cheng, Haibo, Sun, Dongdong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794846/ https://www.ncbi.nlm.nih.gov/pubmed/36591497 http://dx.doi.org/10.3389/fonc.2022.1055126 |
Ejemplares similares
-
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
por: Taherzadeh-Fard, Elahe, et al.
Publicado: (2011) -
Lipoxin A4 attenuated dexamethasone-induced muscle atrophy via activation of PGC-1α/Nrf2/TFAM pathway
por: Rizk, Fatma H., et al.
Publicado: (2022) -
Edaravone prevents high glucose-induced injury in retinal Müller cells through thioredoxin1 and the PGC-1α/NRF1/TFAM pathway
por: Yin, Juanping, et al.
Publicado: (2021) -
Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM
por: Lan, Linhua, et al.
Publicado: (2017) -
Expression of Mitochondrial Regulators PGC1α and TFAM as Putative Markers of Subtype and Chemoresistance in Epithelial Ovarian Carcinoma
por: Gabrielson, Marike, et al.
Publicado: (2014)