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A synthetic human 3D in vitro lymphoid model enhancing B-cell survival and functional differentiation
To investigate B-cell differentiation and maturation occurring in the germinal center (GC) using in vitro culture systems, key factors and interactions of the GC reaction need to be accurately simulated. This study aims at improving in vitro GC simulation using 3D culture techniques. Human B-cells w...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794978/ https://www.ncbi.nlm.nih.gov/pubmed/36590159 http://dx.doi.org/10.1016/j.isci.2022.105741 |