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Characterization of the acetylation of cyclooxygenase-isozymes and targeted lipidomics of eicosanoids in serum and colon cancer cells by the new aspirin formulation IP1867B versus aspirin in vitro

Background: Aspirin(acetylsalicylic acid, ASA) is recommended for the secondary prevention of atherothrombotic events and has shown anticancer effects. The current enteric-coated drug formulation may reduce aspirin bioavailability. Liquid formulations could improve aspirin pharmacokinetics and pharm...

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Detalles Bibliográficos
Autores principales: Hofling, Ulrika, Tacconelli, Stefania, Contursi, Annalisa, Bruno, Annalisa, Mucci, Matteo, Ballerini, Patrizia, Cohen, Simon, Patrignani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795017/
https://www.ncbi.nlm.nih.gov/pubmed/36588714
http://dx.doi.org/10.3389/fphar.2022.1070277