Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is both a devastating and common disease. Every year in the United States, about 24,500 men and 10,000 women are diagnosed with HCC, and more than half of those diagnosed patients die from this disease. Thus far, conventional therapeutics have not been successful for p...

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Detalles Bibliográficos
Autores principales: LoBianco, Francesca V., Krager, Kimberly J., Johnson, Erica, Godwin, Christopher O., Allen, Antino R., Crooks, Peter A., Compadre, Cesar M., Borrelli, Michael J., Aykin-Burns, Nukhet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795200/
https://www.ncbi.nlm.nih.gov/pubmed/36591540
http://dx.doi.org/10.3389/ftox.2022.936149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795200/
https://www.ncbi.nlm.nih.gov/pubmed/36591540
http://dx.doi.org/10.3389/ftox.2022.936149

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