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Simulation-based inference of differentiation trajectories from RNA velocity fields

We report Cytopath, a method for trajectory inference that takes advantage of transcriptional activity information from the RNA velocity of single cells to perform trajectory inference. Cytopath performs this task by defining a Markov chain model, simulating an ensemble of possible differentiation t...

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Detalles Bibliográficos
Autores principales: Gupta, Revant, Cerletti, Dario, Gut, Gilles, Oxenius, Annette, Claassen, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795361/
https://www.ncbi.nlm.nih.gov/pubmed/36590685
http://dx.doi.org/10.1016/j.crmeth.2022.100359