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Simulation-based inference of differentiation trajectories from RNA velocity fields
We report Cytopath, a method for trajectory inference that takes advantage of transcriptional activity information from the RNA velocity of single cells to perform trajectory inference. Cytopath performs this task by defining a Markov chain model, simulating an ensemble of possible differentiation t...
Autores principales: | Gupta, Revant, Cerletti, Dario, Gut, Gilles, Oxenius, Annette, Claassen, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795361/ https://www.ncbi.nlm.nih.gov/pubmed/36590685 http://dx.doi.org/10.1016/j.crmeth.2022.100359 |
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