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In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
Stem cell engineering of striatal medium spiny neurons (MSNs) is a promising strategy to understand diseases affecting the striatum and for cell-replacement therapies in different neurological diseases. Protocols to generate cells from human pluripotent stem cells (PSCs) are scarce and how well they...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795363/ https://www.ncbi.nlm.nih.gov/pubmed/36590694 http://dx.doi.org/10.1016/j.crmeth.2022.100367 |