In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution

Stem cell engineering of striatal medium spiny neurons (MSNs) is a promising strategy to understand diseases affecting the striatum and for cell-replacement therapies in different neurological diseases. Protocols to generate cells from human pluripotent stem cells (PSCs) are scarce and how well they...

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Detalles Bibliográficos
Autores principales: Conforti, Paola, Bocchi, Vittoria Dickinson, Campus, Ilaria, Scaramuzza, Linda, Galimberti, Maura, Lischetti, Tiziana, Talpo, Francesca, Pedrazzoli, Matteo, Murgia, Alessio, Ferrari, Ivan, Cordiglieri, Chiara, Fasciani, Alessandra, Arenas, Ernest, Felsenfeld, Dan, Biella, Gerardo, Besusso, Dario, Cattaneo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795363/
https://www.ncbi.nlm.nih.gov/pubmed/36590694
http://dx.doi.org/10.1016/j.crmeth.2022.100367

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