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AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury

BACKGROUND: Hypoxia-induced apoptosis is linked to the pathogenesis of myocardial infarction. The role of apoptosis-inducing factor mitochondria associated 1 (AIFM1) in cardiomyocyte injury remains unclear. This study was aimed at probing into the role and the underlying regulatory mechanism of AIFM...

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Detalles Bibliográficos
Autores principales: Zhou, Wugang, Ji, Lv, Liu, Xuqin, Tu, Dan, Shi, Ningning, Yangqu, Wangmu, Chen, Shi, Gao, Pingjin, Zhu, Hong, Ruan, Chengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795367/
https://www.ncbi.nlm.nih.gov/pubmed/34863964
http://dx.doi.org/10.1016/j.bj.2021.11.012