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The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

INTRODUCTION: Many autoimmune diseases are characterized by germinal center (GC)-derived, affinity-matured, class-switched autoantibodies, and strategies to block GC formation and progression are currently being explored clinically. However, extrafollicular responses can also play a role. The aim of...

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Detalles Bibliográficos
Autores principales: Voss, Lasse F., Howarth, Amanda J., Wittenborn, Thomas R., Hummelgaard, Sandra, Juul-Madsen, Kristian, Kastberg, Kristian S., Pedersen, Mathias K., Jensen, Lisbeth, Papanastasiou, Anastasios D., Vorup-Jensen, Thomas, Weyer, Kathrin, Degn, Søren E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795406/
https://www.ncbi.nlm.nih.gov/pubmed/36591222
http://dx.doi.org/10.3389/fimmu.2022.1021370