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The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus
INTRODUCTION: Many autoimmune diseases are characterized by germinal center (GC)-derived, affinity-matured, class-switched autoantibodies, and strategies to block GC formation and progression are currently being explored clinically. However, extrafollicular responses can also play a role. The aim of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795406/ https://www.ncbi.nlm.nih.gov/pubmed/36591222 http://dx.doi.org/10.3389/fimmu.2022.1021370 |