Cargando…

The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

INTRODUCTION: Many autoimmune diseases are characterized by germinal center (GC)-derived, affinity-matured, class-switched autoantibodies, and strategies to block GC formation and progression are currently being explored clinically. However, extrafollicular responses can also play a role. The aim of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Voss, Lasse F., Howarth, Amanda J., Wittenborn, Thomas R., Hummelgaard, Sandra, Juul-Madsen, Kristian, Kastberg, Kristian S., Pedersen, Mathias K., Jensen, Lisbeth, Papanastasiou, Anastasios D., Vorup-Jensen, Thomas, Weyer, Kathrin, Degn, Søren E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795406/ https://www.ncbi.nlm.nih.gov/pubmed/36591222 http://dx.doi.org/10.3389/fimmu.2022.1021370

Ejemplares similares

The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome
por: Al-Aubodah, Tho-Alfakar, et al.
Publicado: (2023)

Comparison of gamma and x-ray irradiation for myeloablation and establishment of normal and autoimmune syngeneic bone marrow chimeras
por: Wittenborn, Thomas Rea, et al.
Publicado: (2021)

Antigen footprint governs activation of the B cell receptor
por: Ferapontov, Alexey, et al.
Publicado: (2023)

Extrafollicular CD4(+) T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease
por: Deng, Ruishu, et al.
Publicado: (2017)

Antigen presentation by B cells enables epitope spreading across an MHC barrier
por: Fahlquist-Hagert, Cecilia, et al.
Publicado: (2023)

Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions
por: Chaturvedi, Sumit K., et al.
Publicado: (2020)

Tumor necrosis factor alpha neutralization attenuates immune checkpoint inhibitor-induced activation of intermediate monocytes in synovial fluid mononuclear cells from patients with inflammatory arthritis
por: Sørensen, Anne Sofie, et al.
Publicado: (2022)

B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation
por: Green, Kenneth, et al.
Publicado: (2021)

Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
por: Mohammad-Beigi, Hossein, et al.
Publicado: (2020)

Extrafollicular Dermal Melanocyte Stem Cells and Melanoma
por: Hoerter, James D., et al.
Publicado: (2012)

Extrafollicular reticulum cells in pathologic lymph nodes.
por: Cho, J., et al.
Publicado: (1994)

Extrafollicular Adenomatoid Odontogenic Tumor: An Unusual Case Presentation
por: Reddy Kundoor, Vinay Kumar, et al.
Publicado: (2016)

Extrafollicular Adenomatoid Odontogenic Tumor of the Mandible: Report of a Case
por: Yilmaz, Nergiz, et al.
Publicado: (2009)

An Extrafollicular Adenomatoid Odontogenic Tumor Mimicking a Periapical Cyst
por: Mosavat, Farzaneh, et al.
Publicado: (2018)

Structural Immunology of Complement Receptors 3 and 4
por: Vorup-Jensen, Thomas, et al.
Publicado: (2018)

Mitochondrial regulation of acute extrafollicular B‐cell responses to COVID‐19 severity
por: Cao, Tianyu, et al.
Publicado: (2022)

Extrafollicular proliferation of B‐blasts: Morphologic correlate to Spikevax‐induced lymphadenopathy
por: Tzankov, Alexandar, et al.
Publicado: (2022)

Extrafollicular Cystic Adenomatoid Odontogenic Tumor Misdiagnosed as Glandular Odontogenic Cyst
por: Mashhadiabbas, Fatemeh, et al.
Publicado: (2022)

Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB
por: Nielsen, Morten Aagaard, et al.
Publicado: (2022)

Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer’s disease
por: Parbo, Peter, et al.
Publicado: (2020)

RANK-C Expression Sensitizes ER-Negative, EGFR-Positive Breast Cancer Cells to EGFR-Tyrosine Kinase Inhibitors (TKIs)
por: Sirinian, Chaido, et al.
Publicado: (2021)

Domestic water supply in rural Greenland – sufficiency, affordability and accessibility
por: Maréchal, Judith Y. A., et al.
Publicado: (2022)

Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques
por: Wodarz, Dominik, et al.
Publicado: (2018)

Surgical Management of Extrafollicular Variant of Adenomatoid Odontogenic Tumor in the Maxillary Posterior Region
por: La Monaca, Gerardo, et al.
Publicado: (2019)

Extrafollicular Adenomatoid Odontogenic Tumor in the Maxillary Incisor Region Disguised as Gingival Swelling
por: Saini, Natasha, et al.
Publicado: (2020)

Expansion of extrafollicular B and T cell subsets in childhood-onset systemic lupus erythematosus
por: Baxter, Ryan M., et al.
Publicado: (2023)

Principles for Just Prioritization of Expensive Biological Therapies in the Danish Healthcare System
por: Bladt, Tara, et al.
Publicado: (2023)

Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules
por: Bech, Rikke, et al.
Publicado: (2016)

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
por: Lee, Sau K., et al.
Publicado: (2011)

Nanomedicine
por: Howard, Kenneth A, et al.
Publicado: (2016)

Glatiramer Acetate in Treatment of Multiple Sclerosis: A Toolbox of Random Co-Polymers for Targeting Inflammatory Mechanisms of both the Innate and Adaptive Immune System?
por: Jalilian, Babak, et al.
Publicado: (2012)

An extrafollicular pathway for the generation of effector CD8(+) T cells driven by the proinflammatory cytokine, IL-12
por: Shah, Suhagi, et al.
Publicado: (2015)

Case Report: Gene expression profiling of COVID-19 vaccination-related lymphadenopathies reveals evidence of a dominantly extrafollicular immune response
por: Menter, Thomas, et al.
Publicado: (2023)

Viral Superantigen Drives Extrafollicular and Follicular B Cell Differentiation Leading to Virus-specific Antibody Production
por: Luther, Sanjiv A., et al.
Publicado: (1997)

Extrafollicular B cell activation by marginal zone dendritic cells drives T cell–dependent antibody responses
por: Chappell, Craig P., et al.
Publicado: (2012)

Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa
por: Corrado, Alessia, et al.
Publicado: (2021)

Early IgE Production Is Linked with Extrafollicular B- and T-Cell Activation in Low-Dose Allergy Model
por: Chudakov, Dmitrii Borisovich, et al.
Publicado: (2022)

HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway
por: Krause, Robert, et al.
Publicado: (2022)

Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses
por: Lam, Jonathan H., et al.
Publicado: (2023)

A simple set of validation steps identifies and removes false results in a sandwich enzyme-linked immunosorbent assay caused by anti-animal IgG antibodies in plasma from arthritis patients
por: Kragstrup, Tue W, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_lcdba8qa6k09u1gajahol485ud