Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair

In both humans and mice, repair of acute kidney injury is worse in males than in females. Here, we provide evidence that this sexual dimorphism results from sex differences in ferroptosis, an iron-dependent, lipid-peroxidation-driven regulated cell death. Using genetic and single-cell transcriptomic...

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Detalles Bibliográficos
Autores principales: Ide, Shintaro, Ide, Kana, Abe, Koki, Kobayashi, Yoshihiko, Kitai, Hiroki, McKey, Jennifer, Strausser, Sarah A., O’Brien, Lori L., Tata, Aleksandra, Tata, Purushothama Rao, Souma, Tomokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795409/
https://www.ncbi.nlm.nih.gov/pubmed/36351395
http://dx.doi.org/10.1016/j.celrep.2022.111610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795409/
https://www.ncbi.nlm.nih.gov/pubmed/36351395
http://dx.doi.org/10.1016/j.celrep.2022.111610

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