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Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites

The ubiquitination/proteasome system is important for the spatiotemporal control of protein synthesis and degradation at synapses, while dysregulation may underlie autism spectrum disorders (ASDs). However, methods allowing direct visualization of the subcellular localization and temporal dynamics o...

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Detalles Bibliográficos
Autores principales: Ifrim, Marius F., Janusz-Kaminska, Aleksandra, Bassell, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795412/
https://www.ncbi.nlm.nih.gov/pubmed/36384114
http://dx.doi.org/10.1016/j.celrep.2022.111658