Biomimetic Total Synthesis and the Biological Evaluation of Natural Product (−)-Fargesone A as a Novel FXR Agonist

[Image: see text] Farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, plays an important role in maintaining or reversing metabolic homeostasis during the development of liver diseases. However, developing FXR modulators to intervene in FXR-related diseases is still an unmet cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Fusheng, Chen, Kaiqi, Dong, Haoran, Hu, Dachao, Gao, Yihui, Liu, Chendi, Laphookhieo, Surat, Lei, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795464/
https://www.ncbi.nlm.nih.gov/pubmed/36590256
http://dx.doi.org/10.1021/jacsau.2c00600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795464/
https://www.ncbi.nlm.nih.gov/pubmed/36590256
http://dx.doi.org/10.1021/jacsau.2c00600

Ejemplares similares