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Protein import into peroxisomes occurs through a nuclear pore-like phase
Peroxisomes are ubiquitous organelles whose dysfunction causes fatal human diseases. Most peroxisomal proteins are imported from the cytosol in a folded state by the soluble receptor PEX5. How folded cargo crosses the membrane is unknown. Here, we show that peroxisomal import is similar to nuclear t...
Autores principales: | Gao, Yuan, Skowyra, Michael L., Feng, Peiqiang, Rapoport, Tom A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795577/ https://www.ncbi.nlm.nih.gov/pubmed/36520918 http://dx.doi.org/10.1126/science.adf3971 |
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