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Axl regulated survival/proliferation network and its therapeutic intervention in mouse models of glomerulonephritis

BACKGROUND: Lupus nephritis (LN) is the most common and serious complication of systemic lupus erythematosus (SLE). LN pathogenesis is not fully understood. Axl receptor tyrosine kinase is upregulated and contributes to the pathogenic progress in LN. We have reported that Axl disruption attenuates n...

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Detalles Bibliográficos
Autores principales: Zhen, Yuxuan, Ren, Yan, Medvedovic, Mario, Adams, David E., Wang, Diping, Shao, Wen-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795606/
https://www.ncbi.nlm.nih.gov/pubmed/36578056
http://dx.doi.org/10.1186/s13075-022-02965-w