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Ntrk1 promotes mesangial cell proliferation and inflammation in rat glomerulonephritis model by activating the STAT3 and p38/ERK MAPK signaling pathways

BACKGROUND: Mesangial proliferative glomerulonephritis (MsPGN) accounts for a main cause of chronic kidney disease (CKD), chronic renal failure and uremia. This paper aimed to examine the effect of Ntrk1 on MsPGN development, so as to identify a novel therapeutic target for MsPGN. METHODS: The MsPGN...

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Detalles Bibliográficos
Autores principales: Dong, Xiongjun, Tang, Yingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795628/
https://www.ncbi.nlm.nih.gov/pubmed/36575400
http://dx.doi.org/10.1186/s12882-022-03001-4