Deamidation-related blood biomarkers show promise for early diagnostics of neurodegeneration

BACKGROUND: The strongest risk factor of neurodegenerative diseases (NDDs) is aging. Spontaneous asparaginyl deamidation leading to formation of isoaspartate (isoAsp) has been correlated with protein aggregation in NDDs. METHODS: Two cohorts consisting of 140 subjects were studied. Cohort 1 containe...

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Detalles Bibliográficos
Autores principales: Wang, Jijing, Zhang, Ya-Ru, Shen, Xue-Ning, Han, Jinming, Cui, Mei, Tan, Lan, Dong, Qiang, Zubarev, Roman A., Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795668/
https://www.ncbi.nlm.nih.gov/pubmed/36575499
http://dx.doi.org/10.1186/s40364-022-00435-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795668/
https://www.ncbi.nlm.nih.gov/pubmed/36575499
http://dx.doi.org/10.1186/s40364-022-00435-8

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