Small molecule-mediated rapid maturation of human induced pluripotent stem cell-derived cardiomyocytes

BACKGROUND: Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iPSC-CMs) do not display all hallmarks of mature primary cardiomyocytes, especially the ability to use fatty acids (FA) as an energy source, containing high mitochondrial mass, presenting binucleation and increased DNA co...

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Detalles Bibliográficos
Autores principales: Chirico, Nino, Kessler, Elise L., Maas, Renée G. C., Fang, Juntao, Qin, Jiabin, Dokter, Inge, Daniels, Mark, Šarić, Tomo, Neef, Klaus, Buikema, Jan-Willem, Lei, Zhiyong, Doevendans, Pieter A., Sluijter, Joost P. G., van Mil, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795728/
https://www.ncbi.nlm.nih.gov/pubmed/36575473
http://dx.doi.org/10.1186/s13287-022-03209-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795728/
https://www.ncbi.nlm.nih.gov/pubmed/36575473
http://dx.doi.org/10.1186/s13287-022-03209-z

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