Different coatings on magnetic nanoparticles dictate their degradation kinetics in vivo for 15 months after intravenous administration in mice

BACKGROUND: The surface coating of iron oxide magnetic nanoparticle (MNPs) drives their intracellular trafficking and degradation in endolysosomes, as well as dictating other cellular outcomes. As such, we assessed whether MNP coatings might influence their biodistribution, their accumulation in cer...

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Detalles Bibliográficos
Autores principales: Portilla, Yadileiny, Fernández-Afonso, Yilian, Pérez-Yagüe, Sonia, Mulens-Arias, Vladimir, Morales, M. Puerto, Gutiérrez, Lucía, Barber, Domingo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795732/
https://www.ncbi.nlm.nih.gov/pubmed/36578018
http://dx.doi.org/10.1186/s12951-022-01747-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795732/
https://www.ncbi.nlm.nih.gov/pubmed/36578018
http://dx.doi.org/10.1186/s12951-022-01747-5

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