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Microglial Pten safeguards postnatal integrity of the cortex and sociability

Microglial abnormalities may contribute to neurodevelopmental disorders. PTEN is implicated as a susceptibility gene for autism spectrum disorders and its germline ablation in mice causes behavioral abnormalities. Here we find postnatal PTEN deletion in microglia causes deficits in sociability and n...

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Detalles Bibliográficos
Autores principales: Zhou, Xing, Wei, Jiacheng, Li, Liang, Shu, Zhenfeng, You, Ling, Liu, Yang, Zhao, Ruozhu, Yao, Jiacheng, Wang, Jianbin, Luo, Minmin, Shu, Yousheng, Yuan, Kexin, Qi, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795847/
https://www.ncbi.nlm.nih.gov/pubmed/36591296
http://dx.doi.org/10.3389/fimmu.2022.1059364