Inclusion complexes of the steroid hormones 17β-estradiol and progesterone with β- and γ-cyclodextrin hosts: syntheses, X-ray structures, thermal analyses and API solubility enhancements

Overcoming the challenges of poor aqueous solubility of active pharmaceutical ingredients (APIs) is necessary to render them bioavailable. This study addresses the poor solubility of two potent steroid hormones, 17β-estradiol (BES) and progesterone (PRO), via their complexation with two water-solubl...

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Detalles Bibliográficos
Autores principales: Vicatos, Alexios I, Hoossen, Zakiena, Caira, Mino R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795861/
https://www.ncbi.nlm.nih.gov/pubmed/36628264
http://dx.doi.org/10.3762/bjoc.18.184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795861/
https://www.ncbi.nlm.nih.gov/pubmed/36628264
http://dx.doi.org/10.3762/bjoc.18.184

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