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Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor

BACKGROUND AND AIMS: Hydrogen sulfide (H(2)S) plays a protective role in NAFLD. However, whether cystathionine γ lyase (CSE), a dominant H(2)S generating enzyme in hepatocytes, has a role in the pathogenesis of NAFLD is currently unclear. APPROACH AND RESULTS: We showed that CSE protein expression i...

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Detalles Bibliográficos
Autores principales: Xu, Wenjing, Cui, Changting, Cui, Chunmei, Chen, Zhenzhen, Zhang, Haizeng, Cui, Qinghua, Xu, Guoheng, Fan, Jianglin, Han, Yu, Tang, Liangjie, Targher, Giovanni, Byrne, Christopher D., Zheng, Ming‐Hua, Yang, Liming, Cai, Jun, Geng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795901/
https://www.ncbi.nlm.nih.gov/pubmed/35586979
http://dx.doi.org/10.1002/hep.32577