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Extracellular vesicles from amniotic fluid, milk, saliva, and urine expose complexes of tissue factor and activated factor VII

BACKGROUND: Tissue factor (TF) is expressed in the adventitia of the vessel wall and on extracellular vesicles (EVs) in body fluids. TF and activated coagulation factor (F) VII(a) together form the so‐called extrinsic tenase complex, which initiates coagulation. AIM: We investigated whether EVs in a...

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Detalles Bibliográficos
Autores principales: Hu, Yong, Repa, Andreas, Lisman, Ton, Yerlikaya‐Schatten, Guelen, Hau, Chi, Pabinger, Ingrid, Ay, Cihan, Nieuwland, Rienk, Thaler, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795922/
https://www.ncbi.nlm.nih.gov/pubmed/35748324
http://dx.doi.org/10.1111/jth.15801