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Tumor Necrosis Factor-α Blunts the Osteogenic Effects of Muscle Cell-Derived Extracellular Vesicles by Affecting Muscle Cells

Extracellular vesicles (EVs) play crucial roles in physiological and pathophysiological processes. Although studies have described muscle–bone interactions via humoral factors, we reported that EVs from C2C12 muscle cells (Myo-EVs) suppress osteoclast formation. Current clinical evidence suggests th...

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Detalles Bibliográficos
Autores principales: Takada, Yuto, Takafuji, Yoshimasa, Mizukami, Yuya, Ohira, Takashi, Kawao, Naoyuki, Okada, Kiyotaka, Kaji, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795943/
https://www.ncbi.nlm.nih.gov/pubmed/36576505
http://dx.doi.org/10.1007/s00223-022-01056-x