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Population Pharmacokinetics of Heptanoate in Healthy Subjects and Patients With Long‐Chain Fatty Acid Oxidation Disorders Treated With Triheptanoin

Triheptanoin is an odd‐carbon, medium‐chain triglyceride consisting of three fatty acids with seven carbons each on a glycerol backbone, indicated for the treatment of adult and pediatric patients with long‐chain fatty acid oxidation disorders (LC‐FAOD). A total of 562 plasma concentrations of hepta...

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Detalles Bibliográficos
Autores principales: Lee, Sun Ku, Gosselin, Nathalie H., Jomphe, Claudia, McKeever, Kathleen, Putnam, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795984/
https://www.ncbi.nlm.nih.gov/pubmed/35908210
http://dx.doi.org/10.1002/cpdd.1145