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Antiretroviral therapy restores the homeostatic state of microglia in SIV‐infected rhesus macaques

Microglia and macrophages are essential for homeostatic maintenance and innate immune response in the brain. They are the first line of defense against infections such as HIV/SIV in the brain. However, they are susceptible to infection and function as viral reservoirs even under effective viral supp...

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Detalles Bibliográficos
Autores principales: Trease, Andrew J., Niu, Meng, Morsey, Brenda, Guda, Chittibabu, Byrareddy, Siddappa N., Buch, Shilpa, Fox, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796061/
https://www.ncbi.nlm.nih.gov/pubmed/35686500
http://dx.doi.org/10.1002/JLB.3HI0422-635R