Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: Associations in a large community cohort

BACKGROUND: The iron overload condition hereditary hemochromatosis (HH) can cause liver cirrhosis and cancer, diabetes, and arthritis. Males homozygous for the p.C282Y missense mutation in the Homeostatin Iron Regulator (HFE) gene have greatest risk; yet, only a minority develop these conditions. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilling, Luke C., Atkins, Janice L., Melzer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796074/
https://www.ncbi.nlm.nih.gov/pubmed/35567766
http://dx.doi.org/10.1002/hep.32575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796074/
https://www.ncbi.nlm.nih.gov/pubmed/35567766
http://dx.doi.org/10.1002/hep.32575

Ejemplares similares