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Fusion of two unrelated protein domains in a chimera protein and its 3D prediction: Justification of the x‐ray reference structures as a prediction benchmark

Proteins are naturally formed by domains edging their functional and structural properties. A domain out of the context of an entire protein can retain its structure and to some extent also function on its own. These properties rationalize construction of artificial fusion multidomain proteins with...

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Detalles Bibliográficos
Autores principales: Vymětal, Jiří, Mertová, Kateřina, Boušová, Kristýna, Šulc, Josef, Tripsianes, Konstantinos, Vondrasek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796088/
https://www.ncbi.nlm.nih.gov/pubmed/35833233
http://dx.doi.org/10.1002/prot.26398