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Recombinant multimeric dog allergen prevents airway hyperresponsiveness in a model of asthma marked by vigorous T(H)2 and T(H)17 cell responses

BACKGROUND: Allergy to dogs affects around 10% of the population in developed countries. Immune therapy of allergic patients with dog allergen extracts has shown limited therapeutic benefit. METHODS: We established a mouse model of dog allergy by repeatedly administering dog dander and epithelium ex...

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Detalles Bibliográficos
Autores principales: Stark, Julian M., Liu, Jielu, Tibbitt, Christopher A., Christian, Murray, Ma, Junjie, Wintersand, Anna, Dunst, Josefine, Kreslavsky, Taras, Murrell, Ben, Adner, Mikael, Grönlund, Hans, Gafvelin, Guro, Coquet, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796107/
https://www.ncbi.nlm.nih.gov/pubmed/35657107
http://dx.doi.org/10.1111/all.15399