Beneficial effect of ursodeoxycholic acid in patients with acyl‐CoA oxidase 2 (ACOX2) deficiency–associated hypertransaminasemia

BACKGROUND AND AIMS: A variant (p.Arg225Trp) of peroxisomal acyl‐CoA oxidase 2 (ACOX2), involved in bile acid (BA) side‐chain shortening, has been associated with unexplained persistent hypertransaminasemia and accumulation of C27‐BAs, mainly 3α,7α,12α‐trihydroxy‐5β‐cholestanoic acid (THCA). We aime...

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Detalles Bibliográficos
Autores principales: Alonso‐Peña, Marta, Espinosa‐Escudero, Ricardo, Herraez, Elisa, Briz, Oscar, Cagigal, Maria Luisa, Gonzalez‐Santiago, Jesus M., Ortega‐Alonso, Aida, Fernandez‐Rodriguez, Conrado, Bujanda, Luis, Calvo Sanchez, Marta, D´Avola, Delia, Londoño, Maria‐Carlota, Diago, Moises, Fernandez‐Checa, Jose C., Garcia‐Ruiz, Carmen, Andrade, Raul J., Lammert, Frank, Prieto, Jesus, Crespo, Javier, Juamperez, Javier, Diaz‐Gonzalez, Alvaro, Monte, Maria J., Marin, Jose J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796151/
https://www.ncbi.nlm.nih.gov/pubmed/35395098
http://dx.doi.org/10.1002/hep.32517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796151/
https://www.ncbi.nlm.nih.gov/pubmed/35395098
http://dx.doi.org/10.1002/hep.32517

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