Cargando…

Beneficial effect of ursodeoxycholic acid in patients with acyl‐CoA oxidase 2 (ACOX2) deficiency–associated hypertransaminasemia

BACKGROUND AND AIMS: A variant (p.Arg225Trp) of peroxisomal acyl‐CoA oxidase 2 (ACOX2), involved in bile acid (BA) side‐chain shortening, has been associated with unexplained persistent hypertransaminasemia and accumulation of C27‐BAs, mainly 3α,7α,12α‐trihydroxy‐5β‐cholestanoic acid (THCA). We aime...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alonso‐Peña, Marta, Espinosa‐Escudero, Ricardo, Herraez, Elisa, Briz, Oscar, Cagigal, Maria Luisa, Gonzalez‐Santiago, Jesus M., Ortega‐Alonso, Aida, Fernandez‐Rodriguez, Conrado, Bujanda, Luis, Calvo Sanchez, Marta, D´Avola, Delia, Londoño, Maria‐Carlota, Diago, Moises, Fernandez‐Checa, Jose C., Garcia‐Ruiz, Carmen, Andrade, Raul J., Lammert, Frank, Prieto, Jesus, Crespo, Javier, Juamperez, Javier, Diaz‐Gonzalez, Alvaro, Monte, Maria J., Marin, Jose J. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796151/ https://www.ncbi.nlm.nih.gov/pubmed/35395098 http://dx.doi.org/10.1002/hep.32517

Ejemplares similares

Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation
por: Alonso-Peña, Marta, et al.
Publicado: (2022)

Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
por: Caballero‐Camino, Francisco J., et al.
Publicado: (2020)

The etiology of hypertransaminasemia in Turkish children
por: Serdaroglu, Filiz, et al.
Publicado: (2016)

From hypertransaminasemia to mucopolysaccharidosis IIIA
por: Krawiec, Paulina, et al.
Publicado: (2014)

Mild Hypertransaminasemia in Primary Care
por: Al-Busafi, Said A., et al.
Publicado: (2013)

Early Hypertransaminasemia after Kidney Transplantation: Significance and Evolution According to Donor Type
por: Solà-Porta, Eulàlia, et al.
Publicado: (2021)

Hypertransaminasemia and hypophosphoremia in an adolescent with anorexia nervosa: an event to watch for
por: Marchili, Maria Rosaria, et al.
Publicado: (2016)

Safety and efficacy of cyclin-dependent kinase inhibitor rechallenge following ribociclib-induced limiting hypertransaminasemia
por: Fuentes-Antrás, Jesús, et al.
Publicado: (2020)

PReS-FINAL-1005: Hypertransaminasemia in systemic juvenile idiopathic arthritis during anti-interleukin 1 treatment
por: Gonzalez Fernandez, MI, et al.
Publicado: (2013)

Hypertransaminasemia and fatal lung disease: a case report
por: Santamaria, Francesca, et al.
Publicado: (2013)

The Effects of Gluten-Free Diet on Hypertransaminasemia in Patients with Celiac Disease
por: Moghaddam, Mostafa Alavi, et al.
Publicado: (2013)

Incidental hypertransaminasemia in children—a stepwise approach in primary care
por: Costa, Joana Meneses, et al.
Publicado: (2023)

Acox2 is a regulator of lysine crotonylation that mediates hepatic metabolic homeostasis in mice
por: Zhang, Yuan, et al.
Publicado: (2022)

Altered expression of ACOX2 in non-small cell lung cancer
por: Sui, Jane S. Y., et al.
Publicado: (2022)

Looking Into the Crystal Ball: Predicting Non-response to Ursodeoxycholic Acid in Primary Biliary Cholangitis
por: Zimmer, Vincent, et al.
Publicado: (2016)

The effect of Helicobacter pylori eradication on liver enzymes in patients referring with unexplained hypertransaminasemia
por: Salehi, Hassan, et al.
Publicado: (2014)

Hypertransaminasemia in the course of infection with SARS-CoV-2: Incidence and pathogenetic hypothesis
por: Zippi, Maddalena, et al.
Publicado: (2020)

ACOX-driven peroxisomal heterogeneity and functional compartmentalization in brown adipocytes of hypothyroid rats
por: Aleksic, Marija, et al.
Publicado: (2023)

Intelligent tutoring systems for word problem solving in COVID-19 days: could they have been (part of) the solution?
por: del Olmo-Muñoz, Javier, et al.
Publicado: (2022)

Celiac Disease in Conjunction with Hereditary Fructose Intolerance as a Rare Cause of Liver Steatosis with Mild Hypertransaminasemia—A Case Report
por: Bobrus-Chociej, Anna, et al.
Publicado: (2021)

TRANS-TACE: Prognostic Role of the Transient Hypertransaminasemia after Conventional Chemoembolization for Hepatocellular Carcinoma
por: Granito, Alessandro, et al.
Publicado: (2021)

Distribution of DNA damage in the human sperm nucleus: implications of the architecture of the sperm head
por: González-Rojo, Silvia, et al.
Publicado: (2019)

Genetic and epigenetic alterations induced by bisphenol A exposure during different periods of spermatogenesis: from spermatozoa to the progeny
por: Lombó, Marta, et al.
Publicado: (2019)

c.761C>T Mutation Linked Hyper IgM Syndrome Presenting with Hypertransaminasemia and Arthritis
por: Celiksoy, Mehmet Halil, et al.
Publicado: (2014)

Risk of Statin-Induced Hypertransaminasemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
por: Villani, Rosanna, et al.
Publicado: (2019)

Variability of ACOX1 Gene Polymorphisms across Different Horse Breeds with Regard to Selection Pressure
por: Myćka, Grzegorz, et al.
Publicado: (2020)

Loss of ACOX1 in clear cell renal cell carcinoma and its correlation with clinical features
por: Mo, Yingxi, et al.
Publicado: (2023)

Haplotypes of intron 4 of the estrogen receptor alpha gene and hip fractures: a replication study in Caucasians
por: Velasco, Javier, et al.
Publicado: (2010)

Accuracy of the 2008 Simplified Criteria for the Diagnosis of Autoimmune Hepatitis in Children
por: Arcos-Machancoses, José Vicente, et al.
Publicado: (2018)

Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer
por: Martínez-González, Luis Javier, et al.
Publicado: (2021)

Ursodeoxycholic Acid Is Conjugated with Taurine to Promote Secretin-Stimulated Biliary Hydrocholeresis in the Normal Rat
por: Úriz, Miriam, et al.
Publicado: (2011)

Successful Treatment with Rituximab and Immunoadsorption for an Auto-Antibody Induced Bile Salt Export Pump Deficiency in a Liver Transplanted Patient
por: Quintero, Jesús, et al.
Publicado: (2020)

ACOX2 is a prognostic marker and impedes the progression of hepatocellular carcinoma via PPARα pathway
por: Zhang, Qifan, et al.
Publicado: (2021)

Closure of oroantral communications with Bichat´s buccal fat pad. Level of patient satisfaction
por: Alonso-González, Rocío, et al.
Publicado: (2015)

Fatty liver disease and hypertransaminasemia hiding the association of clinically silent Duchenne muscular dystrophy and hereditary fructose intolerance
por: Paolella, Giulia, et al.
Publicado: (2012)

Deporte y agresión /
por: Cagigal, José María
Publicado: (1990)

{Uhorn}Oh deporte! : anatomía de un gigante
por: Cagigal, José María
Publicado: (1981)

Cultura intelectual y cultura física
por: Cagigal, José María
Publicado: (1979)

Musculoskeletal disorders: OWAS review
por: GÓMEZ-GALÁN, Marta, et al.
Publicado: (2017)

Effect of Propolis Paste and Mouthwash Formulation on Healing after Teeth Extraction in Periodontal Disease
por: Lisbona-González, Maria Jesús, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cr6veq2rbuq7imensmbcdlujif