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Efficacy and safety of N‐acetyl‐GED‐0507‐34‐LEVO gel in patients with moderate‐to severe facial acne vulgaris: a phase IIb randomized double‐blind, vehicle‐controlled trial

BACKGROUND: Preliminary in vitro and in vivo studies have supported the efficacy of the peroxisome proliferator‐activated receptor‐γ (PPARγ) modulator N‐acetyl‐GED‐0507‐34‐LEVO (NAC‐GED) for the treatment of acne‐inducing sebocyte differentiation, improving sebum composition and controlling the infl...

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Detalles Bibliográficos
Autores principales: Picardo, Mauro, Cardinali, Carla, La Placa, Michelangelo, Lewartowska‐Białek, Anita, Lora, Viviana, Micali, Giuseppe, Montisci, Roberta, Morbelli, Luca, Nova, Andrea, Parodi, Aurora, Reich, Adam, Sebastian, Michael, Turek‐Urasińska, Katarzyna, Weirich, Oliver, Zdybski, Jacek, Zouboulis, Christos C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796277/
https://www.ncbi.nlm.nih.gov/pubmed/35553043
http://dx.doi.org/10.1111/bjd.21663