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Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function

AIMS: Chronic kidney disease (CKD) is common and cardiovascular disease (CVD) is its commonest complication. The apelin system is a potential therapeutic target for CVD but data relating to apelin in CKD are limited. We examined expression of the apelin system in human kidney, and investigated apeli...

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Detalles Bibliográficos
Autores principales: Nyimanu, Duuamene, Chapman, Fiona A., Gallacher, Peter J., Kuc, Rhoda E., Williams, Thomas L., Newby, David E., Maguire, Janet J., Davenport, Anthony P., Dhaun, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796317/
https://www.ncbi.nlm.nih.gov/pubmed/35748053
http://dx.doi.org/10.1111/bcp.15446