An expanded access protocol of RT001 in amyotrophic lateral sclerosis—Initial experience with a lipid peroxidation inhibitor

INTRODUCTION/AIMS: Lipid peroxidation is thought to play a biologically important role in motor neuron death in amyotrophic lateral sclerosis (ALS). 11,11 Di‐deuterated linoleic ethyl ester (RT001) prevents lipid peroxidation in cellular and mitochondrial membranes. Herein we report on the use of RT...

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Detalles Bibliográficos
Autores principales: Yerton, Megan, Winter, Allison, Kostov, Anthony, Lieberman, Cassandra, Gelevski, Dario, Weber, Harli, Doyle, Michael, Kane, Geli, Parikh, Neil, Burke, Katherine M., Rohrer, Margot, Stirrat, Taylor, Bruno, Margaret, Hochman, Alison, Luppino, Sarah, Scalia, Jennifer, Skoniecki, Debra, D'Agostino, Derek, Sinani, Ervin, Yu, Hong, Sherman, Alexander V., Babu, Suma, Berry, James D., Midei, Mark G., Milner, Peter G., Cudkowicz, Merit E., Paganoni, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Clinical Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796343/
https://www.ncbi.nlm.nih.gov/pubmed/35765222
http://dx.doi.org/10.1002/mus.27672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796343/
https://www.ncbi.nlm.nih.gov/pubmed/35765222
http://dx.doi.org/10.1002/mus.27672

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