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Early Changes in Striatal Activity and Motor Kinematics in a Huntington's Disease Mouse Model

BACKGROUND: Huntington's disease is a progressive neurodegenerative disorder with no disease‐modifying treatments. Patients experience motor, cognitive, and psychiatric disturbances, and the dorsal striatum is the main target of neurodegeneration. Mouse models of Huntington's disease show...

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Detalles Bibliográficos
Autores principales: Koch, Ellen T., Sepers, Marja D., Cheng, Judy, Raymond, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796416/
https://www.ncbi.nlm.nih.gov/pubmed/35880748
http://dx.doi.org/10.1002/mds.29168