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The interaction between the Dbf4 ortholog Chiffon and Gcn5 is conserved in Dipteran insect species

Chiffon is the sole Drosophila ortholog of Dbf4, the regulatory subunit for the cell‐cycle kinase Cdc7 that initiates DNA replication. In Drosophila, the chiffon gene encodes two polypeptides with independent activities. Chiffon‐A contains the conserved Dbf4 motifs and interacts with Cdc7 to form th...

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Detalles Bibliográficos
Autores principales: George, Smitha, Blum, Hannah R., Torres‐Zelada, Eliana F., Estep, Grace N., Hegazy, Youssef A., Speer, Gina M., Weake, Vikki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796610/
https://www.ncbi.nlm.nih.gov/pubmed/35789507
http://dx.doi.org/10.1111/imb.12800