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Sepsis, pyruvate, and mitochondria energy supply chain shortage

Balancing high energy‐consuming danger resistance and low energy supply of disease tolerance is a universal survival principle that often fails during sepsis. Our research supports the concept that sepsis phosphorylates and deactivates mitochondrial pyruvate dehydrogenase complex control over the tr...

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Detalles Bibliográficos
Autores principales: McCall, Charles E., Zhu, Xuewei, Zabalawi, Manal, Long, David, Quinn, Matthew A., Yoza, Barbara K., Stacpoole, Peter W., Vachharajani, Vidula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796618/
https://www.ncbi.nlm.nih.gov/pubmed/35866365
http://dx.doi.org/10.1002/JLB.3MR0322-692RR