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Sepsis, pyruvate, and mitochondria energy supply chain shortage
Balancing high energy‐consuming danger resistance and low energy supply of disease tolerance is a universal survival principle that often fails during sepsis. Our research supports the concept that sepsis phosphorylates and deactivates mitochondrial pyruvate dehydrogenase complex control over the tr...
Autores principales: | McCall, Charles E., Zhu, Xuewei, Zabalawi, Manal, Long, David, Quinn, Matthew A., Yoza, Barbara K., Stacpoole, Peter W., Vachharajani, Vidula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796618/ https://www.ncbi.nlm.nih.gov/pubmed/35866365 http://dx.doi.org/10.1002/JLB.3MR0322-692RR |
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